Obsessive-compulsive disorder and 5-HTTLPR.
نویسندگان
چکیده
Referências 1. Rowe DL. Off-label prescription of quetiapine in psychiatric disorders. Expert Rev Neurother. 2007;7(7):841-52. 2. Rachid F, Bertschy G, Bondolfi G, Aubry JM. Possible induction of mania or hypomania by atypical antipsychotics: an updated review of reported cases. J Clin Psychiatry. 2004;65(11):1537-45. 3. McIntyre A, Gendron A, McIntyre A. Quetiapine reduces residual depressive and prominent anxiety symptoms in partial responders to selective serotonin reuptake inhibitors (SSRIs) or serotonin norepinephrine reuptake inhibitors (SNRIs) with major depression:
منابع مشابه
A pilot study exploring the association of morphological changes with 5-HTTLPR polymorphism in OCD patients
BACKGROUND Clinical and pharmacological studies of obsessive-compulsive disorder (OCD) have suggested that the serotonergic systems are involved in the pathogenesis, while structural imaging studies have found some neuroanatomical abnormalities in OCD patients. In the etiopathogenesis of OCD, few studies have performed concurrent assessment of genetic and neuroanatomical variables. METHODS We...
متن کاملA novel, putative gain-of-function haplotype at SLC6A4 associates with obsessive-compulsive disorder.
Obsessive-compulsive disorder (OCD) is a disabling neuropsychiatric illness with strong segregation data indicative of major genetic contributions. Association analyses of common functional variants of the serotonin transporter gene (SLC6A4), a long-standing OCD candidate, have so far been inconsistent. Here, we set out to investigate the role of additional functional SLC6A4 loci in OCD. We des...
متن کاملAssociation of serotonin transporter gene polymorphisms with obsessive-compulsive disorder (OCD) in a south Indian population
BACKGROUND AND OBJECTIVES Serotonin transporter polymorphisms, 5-HTTVNTR and 5-HTTLPR, have been found to be associated with obsessive-compulsive disorder (OCD) and particularly with neurotic characteristics. In the present study we looked for an association between OCD and these polymorphisms in OCD patients and controls of south Indian origin. METHODS 5-HTTVNTR and 5-HTTLPR/rs25531 were gen...
متن کاملThe correlates of diagnostic instability in eating disorders: the role of psychopathology, environmental risk factors, personality and genes
Method Participants were 316 ED patients. The EATATE part 1 (a semi-structured interview) was used to examine diagnostic cross-over in EDs. The Eating Disorder Inventory (EDI-2), Temperament and Character Inventory (TCI-R), Oxford Risk Factor Interview (ORFI), the EATATE part 2 [used to assess obsessive-compulsive personality (OCPD) traits and impulsive behaviours] and four candidate genes (5-H...
متن کاملPrediction of response to paroxetine and venlafaxine by serotonin-related genes in obsessive-compulsive disorder in a randomized, double-blind trial.
OBJECTIVE Serotonin reuptake inhibitors (SRIs) are the most effective pharmacologic treatment currently available for patients with obsessive-compulsive disorder (OCD). Still, up to 40% to 60% of OCD patients do not respond to SRI treatment. The purpose of the present study was to determine whether polymorphisms of the serotonin transporter (5-HTT), 5-HT1B, and 5-HT2A receptor genes affect the ...
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ورودعنوان ژورنال:
- Revista brasileira de psiquiatria
دوره 31 3 شماره
صفحات -
تاریخ انتشار 2009